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WEIGHT & METABOLIC HEALTH
Weight care that includes the medicine.

GLP-1 programs directed by a licensed clinician, with the medication included in the price. No separate pharmacy bill, no membership fee, no insurance to fight with.

$100 off your first month Medication included HSA/FSA eligible
An everyday morning at home
FROM
$275/mo
On the 2-month semaglutide package. Medication included.
WEIGHT & METABOLIC HEALTH

Weight care that includes the medicine.

GLP-1 programs directed by a licensed clinician, with the medication included in the price.

See the programs Book a free consult →
$100 off month one Medication included HSA/FSA
An everyday morning at home
FROM
$275/mo
On the 2-month semaglutide package.
TWO PROGRAMS
Both include the medication.
Semaglutide
FROM
$275/mo
2-month package $550

The longer established of the two GLP-1 medications, and the lower price.

$100 off your first month. Medication included.
Start semaglutide
Tirzepatide
FROM
$375/mo
2-month package $750

Acts on GLP-1 and on GIP, a second gut hormone. Tends to be described as the stronger of the two, and costs more.

$100 off your first month. Medication included.
Start tirzepatide

Which one suits you is a clinical decision your clinician makes with you, based on your history and your goals. Not sure? The free consult is for exactly this.

TWO PROGRAMS

Both include the medication.

Semaglutide
FROM
$275/mo
2-month package $550

The longer established of the two GLP-1 medications, and the lower price.

$100 off your first month. Medication included.
Start now
Tirzepatide
FROM
$375/mo
2-month package $750

Acts on GLP-1 and on GIP, a second gut hormone. Tends to be described as the stronger of the two, and costs more.

$100 off your first month. Medication included.
Start now

Not sure which? The free consult is for exactly this.

THE BIOLOGY
It was never about willpower.

When you lose weight, your body treats it as a loss to be recovered. Hunger hormones tend to rise, the hormones that make you feel full tend to fall, and your body gets more economical with the energy it burns. That pull can last a year or more after the weight comes off.

It's why most diets work for a while and then stall, and why the weight so often comes back. It isn't a character flaw. It's physiology doing what it evolved to do.

GLP-1 medications work on that pull directly. That's the difference.
THE PULL BACK
ILLUSTRATIVE
HUNGER SIGNAL rises, and stays up quiet on a GLP-1 BODY WEIGHT the weight comes back holds on a GLP-1 month 1 month 6 month 12
hunger weight on a GLP-1
Illustrative. Not patient data.
THE BIOLOGY

It was never about willpower.

When you lose weight, your body treats it as a loss to be recovered. Hunger hormones tend to rise, the hormones that make you feel full tend to fall, and your body gets more economical with the energy it burns. That pull can last a year or more after the weight comes off.

It's why most diets work for a while and then stall. It isn't a character flaw. It's physiology doing what it evolved to do.

THE PULL BACK
ILLUSTRATIVE
HUNGER SIGNAL rises, and stays up quiet on a GLP-1 BODY WEIGHT the weight comes back holds on a GLP-1 month 1 month 6 month 12
hunger weight on a GLP-1
Illustrative. Not patient data.
GLP-1 medications work on that pull directly. That's the difference.
Three things change at once.

GLP-1 is a hormone your gut releases after you eat. The medications copy it, and last much longer than your own version does.

01
In your brain · fullness arrives sooner.
The signal that says "that's enough" gets louder, and the background noise about food gets quieter.
02
In your stomach · food stays longer.
Your stomach empties more slowly, so a normal meal keeps you satisfied for longer.
03
In your blood · steadier sugar.
Your body releases insulin more appropriately after a meal, which evens out the spikes and dips that drive cravings.
Tirzepatide does all three and also acts on GIP, a second gut hormone.
See them side by side

Three things change at once.

GLP-1 is a hormone your gut releases after you eat. The medications copy it, and last much longer than your own version does.

In your brain · fullness arrives sooner.
The signal that says "that's enough" gets louder, and the background noise about food gets quieter.
In your stomach · food stays longer.
Your stomach empties more slowly, so a normal meal keeps you satisfied for longer.
In your blood · steadier sugar.
Your body releases insulin more appropriately after a meal, which evens out the spikes and dips that drive cravings.
Tirzepatide does all three and also acts on GIP, a second gut hormone.
Semaglutide or tirzepatide.
COMPARED
Semaglutide
Tirzepatide
Acts on
GLP-1
GLP-1 and GIP
Track record
The longer established of the two
The newer of the two
How it's taken
Once-weekly injection at home
Once-weekly injection at home
From, on the 2-month package
$275/mo
$375/mo
Month to month
$299/mo
$399/mo
New patients
$100 off your first month
$100 off your first month
Medication included
Yes
Yes

Your clinician confirms which medication and which formulation suits you at your visit, and it is dispensed through a licensed pharmacy.

Semaglutide or tirzepatide.

Semaglutide
Tirzepatide
ACTS ON
GLP-1
GLP-1 and GIP
TRACK RECORD
The longer established of the two
The newer of the two
FROM, ON THE 2-MONTH PACKAGE
$275/mo
$375/mo
MONTH TO MONTH
$299/mo
$399/mo
HOW IT'S TAKEN
Once-weekly injection at home, both
NEW PATIENTS
$100 off your first month, both

Your clinician confirms which medication and which formulation suits you at your visit, and it is dispensed through a licensed pharmacy.

WHAT THE TRIALS FOUND
The published numbers, without the spin.

These are average results from the large randomized trials of these medications. Averages are not a forecast of what happens to you, and the trials studied FDA-approved medications rather than compounded versions. They're the clearest picture available of what this class of medication does.

HEAD TO HEAD
SURMOUNT-5 · 72 weeks · 751 adults
Average body-weight reduction, the two medications compared directly.
Tirzepatide 20.2% Semaglutide 13.7% 0% 12.5% 25%
AGAINST PLACEBO
STEP 1 · SURMOUNT-1
Average reduction by dose, each against its own placebo group.
Semaglutide 2.4mg 14.9% Tirzepatide 5mg 15.0% Tirzepatide 10mg 19.5% Tirzepatide 15mg 20.9%
Placebo groups averaged 2.4% and 3.1% over the same periods.
HOW MANY PEOPLE REACHED EACH THRESHOLD
SURMOUNT-5 · 72 weeks
Lost 10% or more of body weight
Tirzepatide87.7%
Semaglutide66.7%
Lost 15% or more of body weight
Tirzepatide71.7%
Semaglutide45.0%

Sources: STEP 1, New England Journal of Medicine, 2021, semaglutide 2.4mg over 68 weeks. SURMOUNT-1, New England Journal of Medicine, 2022, tirzepatide 5, 10, and 15mg over 72 weeks. SURMOUNT-5, New England Journal of Medicine, 2025, tirzepatide compared with semaglutide over 72 weeks.

These trials studied FDA-approved branded medications at their highest tolerated maintenance doses, alongside diet and exercise counselling. They did not study compounded medications. Individual results vary, and your clinician will talk through what is realistic for you.

WHAT THE TRIALS FOUND

The published numbers, without the spin.

Average results from the large randomized trials. Averages are not a forecast of what happens to you, and the trials studied FDA-approved medications rather than compounded versions.

HEAD TO HEAD
SURMOUNT-5 · 72 weeks · 751 adults
Tirzepatide20.2%
Semaglutide13.7%
Average body-weight reduction, on a scale to 25%.
AGAINST PLACEBO
STEP 1 · SURMOUNT-1
Semaglutide 2.4mg14.9%
Tirzepatide 5mg15.0%
Tirzepatide 10mg19.5%
Tirzepatide 15mg20.9%
Placebo groups averaged 2.4% and 3.1% over the same periods.
HOW MANY REACHED EACH THRESHOLD
SURMOUNT-5 · 72 weeks
Lost 10% or more
Tirzepatide87.7%
Semaglutide66.7%
Lost 15% or more
Tirzepatide71.7%
Semaglutide45.0%

Sources: STEP 1, New England Journal of Medicine, 2021. SURMOUNT-1, New England Journal of Medicine, 2022. SURMOUNT-5, New England Journal of Medicine, 2025.

These trials studied FDA-approved medications alongside diet and exercise counselling. They did not study compounded medications. Individual results vary.

One price, and it covers the part that usually costs the most.

Most weight programs charge you a membership and then send you to a pharmacy to find out what the medication costs. Refuvia doesn't work that way. The price you see includes the medicine.

01
A visit with a licensed clinician.
They review your history, your goals, and whether a GLP-1 is appropriate for you.
02
Your medication.
Prepared and shipped by a licensed compounding pharmacy, direct to your door. No separate medication fee.
03
Dose adjustments.
Your dose is titrated over time. Changing it is part of the program, not a new appointment to pay for.
04
Ongoing check-ins.
Someone stays with your case rather than writing a prescription and disappearing.

One price, and it covers the part that usually costs the most.

Most weight programs charge you a membership and then send you to a pharmacy to find out what the medication costs. Refuvia doesn't work that way. The price you see includes the medicine.

01
A visit with a licensed clinician.
They review your history, your goals, and whether a GLP-1 is appropriate for you.
02
Your medication.
Prepared and shipped by a licensed compounding pharmacy, direct to your door. No separate medication fee.
03
Dose adjustments.
Your dose is titrated over time. Changing it is part of the program, not a new appointment to pay for.
04
Ongoing check-ins.
Someone stays with your case rather than writing a prescription and disappearing.
Who this tends to suit.
You've lost weight before and it came back, more than once.
Your appetite feels like something you're fighting rather than something you control.
Your weight is affecting your blood sugar, your blood pressure, your joints, or your sleep.
You want medical supervision rather than a subscription box.
You want the medication cost known up front.
How clinicians usually decide.

GLP-1 weight medications are generally considered for adults with a BMI of 30 or more, or 27 or more alongside a weight-related condition such as high blood pressure, high cholesterol, prediabetes, type 2 diabetes, or sleep apnea. Your clinician also checks for the situations where GLP-1s aren't used, including pregnancy and certain thyroid conditions. Treatment is prescribed only when it's medically appropriate, and not everyone qualifies.

CHECK YOUR BMI
Height
5'9"
4'8"6'8"
Weight
212 lb
90 lb400 lb
31.3your BMI
under 2727 to 29.930 and above
GLP-1 treatment is commonly considered at this BMI. Your clinician confirms it at your visit.
Get started
27 to 29.9 · GLP-1 treatment is often considered at this BMI when there's also a weight-related condition, like high blood pressure, high cholesterol, prediabetes, or sleep apnea. Book a free consult →
Under 27 · At this BMI the conversation usually starts with your metabolic picture rather than a GLP-1. The care team can help you work out the right place to begin. Book a free consult →
A screening guide, not a diagnosis. Your clinician makes the decision.

Who this tends to suit.

You've lost weight before and it came back, more than once.
Your appetite feels like something you're fighting rather than something you control.
Your weight is affecting your blood sugar, your blood pressure, your joints, or your sleep.
You want medical supervision rather than a subscription box.
You want the medication cost known up front.
CHECK YOUR BMI
Height
5'9"
4'8"6'8"
Weight
212 lb
90 lb400 lb
31.3your BMI
under 2727 to 29.930+
GLP-1 treatment is commonly considered at this BMI. Your clinician confirms it at your visit.
Get started
A screening guide, not a diagnosis. Your clinician makes the decision.

How clinicians usually decide.

GLP-1 weight medications are generally considered for adults with a BMI of 30 or more, or 27 or more alongside a weight-related condition such as high blood pressure, high cholesterol, prediabetes, type 2 diabetes, or sleep apnea. Treatment is prescribed only when it's medically appropriate, and not everyone qualifies.

From here to your first dose.
Tell us what's going on.
A short intake online. A few minutes.
Meet your clinician.
A telehealth visit to go through your history and goals and decide whether a GLP-1 is right for you.
Start.
If it's appropriate, your prescription goes to a licensed compounding pharmacy and ships to your door. A free session with the care team shows you how to take it.
Adjust as you go.
Your dose is stepped up gradually. Check-ins and adjustments are part of the program.

From here to your first dose.

Tell us what's going on.
A short intake online. A few minutes.
Meet your clinician.
A telehealth visit to go through your history and goals and decide whether a GLP-1 is right for you.
Start.
If it's appropriate, your prescription goes to a licensed compounding pharmacy and ships to your door. A free session with the care team shows you how to take it.
Adjust as you go.
Your dose is stepped up gradually. Check-ins and adjustments are part of the program.
What the first year usually looks like.

Nobody can tell you in advance how much weight you'll lose. What we can tell you is the shape of it, because it's consistent.

THE SHAPE OF A YEAR
ILLUSTRATIVE
Restore
WEEKS 1-8 · TITRATION
The dose starts low and steps up slowly. That's deliberate, and it's how side effects stay manageable.
Transform
MONTHS 2-9 · THE STEEPEST PART
Most of the change people notice happens here. Almost everyone hits a plateau somewhere around month six to nine. It's expected, and it's what your clinician adjusts for.
Thrive
ONGOING · MAINTENANCE
The work shifts from losing to keeping, with check-ins that keep the plan current.
Illustrative. Individual results vary.
Side effects are common early and usually fade.
Nausea, especially in the first weeks after a dose increase. Slower titration is the usual answer.
Muscle matters.
Some of what you lose on a GLP-1 is lean mass. Protein and resistance training are part of the conversation with your clinician, not an afterthought.
Stopping usually means regaining.
These medications treat an ongoing condition. Your clinician will talk through what maintenance looks like before you're near it.

What the first year usually looks like.

Nobody can tell you in advance how much weight you'll lose. What we can tell you is the shape of it, because it's consistent.

THE SHAPE OF A YEAR
ILLUSTRATIVE
Restore
WEEKS 1-8 · TITRATION
The dose starts low and steps up slowly. That's deliberate, and it's how side effects stay manageable.
Transform
MONTHS 2-9 · THE STEEPEST PART
Most of the change people notice happens here. Almost everyone hits a plateau around month six to nine. It's expected, and it's what your clinician adjusts for.
Thrive
ONGOING · MAINTENANCE
The work shifts from losing to keeping, with check-ins that keep the plan current.
Illustrative. Individual results vary.
Side effects are common early and usually fade.
Nausea, especially in the first weeks after a dose increase. Slower titration is the usual answer.
Muscle matters.
Some of what you lose on a GLP-1 is lean mass. Protein and resistance training are part of the conversation with your clinician.
Stopping usually means regaining.
These medications treat an ongoing condition. Your clinician will talk through what maintenance looks like before you're near it.
WHAT HELPS
The medicine quiets the noise. Habits keep the result.

A GLP-1 makes eating less feel normal instead of like a fight. What you do with that quiet is what decides how much of the result you keep.

01
Protein first.
Building meals around protein helps protect the muscle you'd otherwise lose along with fat.
02
Lift something.
Strength training two or three times a week is the other half of keeping muscle. It doesn't have to be a gym.
03
Smaller, slower meals.
Eating slowly and stopping at the first sign of fullness is also the simplest way to keep early nausea down.
04
Water, and sleep.
Staying hydrated eases side effects, and short sleep pushes hunger hormones the wrong way.
Your clinician will talk through all of this with you. Nutrition coaching is coming soon. See all services →
WHAT HELPS

The medicine quiets the noise. Habits keep the result.

A GLP-1 makes eating less feel normal instead of like a fight. What you do with that quiet is what decides how much of the result you keep.

01
Protein first.
Protects the muscle you'd otherwise lose along with fat.
02
Lift something.
Two or three times a week. It doesn't have to be a gym.
03
Smaller, slower meals.
The simplest way to keep early nausea down.
04
Water, and sleep.
Short sleep pushes hunger hormones the wrong way.
Nutrition coaching is coming soon. See all services →
The scale is one number. These are the rest.

Weight is the number people watch, but the markers underneath are where the health change actually shows up. They're optional, and genuinely useful.

Refuvia Baseline Panel
$199
Comprehensive lab testing covering lipids, hormones, thyroid, metabolic markers, A1c, and insulin. Physician-reviewed. A clear picture of where you're starting, and a baseline to compare against later.
Order the panel
Continuous glucose monitor
$149
One time. One 14-day sensor and a clinician visit. See how your body actually responds to what you eat, rather than guessing.
A continuous glucose monitor does not diagnose diabetes.
Start with a sensor
Metformin
$149
For three months, $50 a month. A long-established medication for blood sugar, sometimes used alongside weight care. Your clinician decides whether it fits.
Talk to a clinician

The scale is one number. These are the rest.

Weight is the number people watch, but the markers underneath are where the health change actually shows up.

Refuvia Baseline Panel
$199
Lipids, hormones, thyroid, metabolic markers, A1c, and insulin. Physician-reviewed.
Order the panel
Glucose monitor
$149
One time. One 14-day sensor and a clinician visit. See how your body responds to what you eat.
A continuous glucose monitor does not diagnose diabetes.
Start with a sensor
Metformin
$149
For three months, $50 a month. Sometimes used alongside weight care. Your clinician decides whether it fits.
Talk to a clinician
Once a week, at home.

Both medications are a once-weekly injection just under the skin, with a very fine needle. Most people pick a day of the week and keep it. Your dose starts low and steps up every few weeks, and once your medication arrives a free session with the care team shows you exactly how to take it.

Refuvia dispenses compounded semaglutide and tirzepatide, prepared and shipped by a licensed compounding pharmacy.

The first few weeks.
Eat smaller meals, and stop at the first sign of fullness.
Go easy on greasy and very rich food while your body adjusts.
Keep your water up. It eases the most common side effects.
Build meals around protein, to protect muscle as you lose.

Once a week, at home.

Both medications are a once-weekly injection just under the skin, with a very fine needle. Once your medication arrives, a free session with the care team shows you exactly how to take it.

The first few weeks.

Eat smaller meals, and stop at the first sign of fullness.
Go easy on greasy and very rich food while your body adjusts.
Keep your water up. It eases the most common side effects.
Build meals around protein, to protect muscle as you lose.
Questions about weight care.
How much does weight loss cost at Refuvia?+

Semaglutide is $299 a month and tirzepatide is $399 a month, with $100 off your first month for new patients. Two-month packages bring the monthly rate down to $275 and $375. The medication is included in that price.

Is the medication really included?+

Yes. There is no separate medication fee and no pharmacy bill to pay on top. If a GLP-1 is prescribed, it's prepared and shipped by a licensed compounding pharmacy as part of your program.

What's the difference between semaglutide and tirzepatide?+

They work on different receptors. Semaglutide acts on GLP-1. Tirzepatide acts on both GLP-1 and GIP. Tirzepatide costs more. Which one suits you is a clinical decision your clinician makes with you, based on your history and your goals.

Who qualifies for a GLP-1?+

GLP-1 weight medications are generally considered for adults with a BMI of 30 or more, or 27 or more with a weight-related condition such as high blood pressure or prediabetes. Your clinician makes the final decision based on your full history.

How is it taken?+

Both are a once-weekly injection just under the skin that you do at home. After your medication arrives, a free session with the care team shows you exactly how.

What side effects are common?+

Nausea is the most common, mostly in the first weeks and after a dose increase, and it usually fades. Stepping the dose up slowly, eating smaller meals, and staying hydrated are the usual answers, and your clinician adjusts as you go.

Will I lose muscle?+

Some of the weight lost on a GLP-1 is lean mass. Eating enough protein and doing some strength training are the two most effective ways to protect it, and your clinician will talk through both.

Is this the same medication I've seen advertised?+

The active medications are semaglutide and tirzepatide, the same two molecules behind the GLP-1 treatments you have read about. Your clinician confirms which one suits you and which formulation you are prescribed, and it is dispensed through a licensed pharmacy. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.

Why does tirzepatide cost more than semaglutide?+

It acts on two gut hormones rather than one, and the medication itself costs more to source. Whether the difference is worth it for you is a conversation with your clinician.

How quickly will I see a change?+

Your dose starts low and steps up over the first weeks, so early changes are usually modest. Most people notice appetite changes before they notice anything on the scale. Individual results vary.

Do I need insurance?+

No. Refuvia doesn't bill insurance, so there are no claims, no prior authorizations, and no denials. Most treatments are HSA and FSA eligible.

Do I need labs first?+

Not to begin. Your clinician may recommend the Refuvia Baseline Panel to see your metabolic markers before or during treatment, but it isn't a gate you have to clear before starting.

What happens if I stop?+

GLP-1 medications treat an ongoing condition, and appetite usually returns when they stop. Your clinician will talk through maintenance with you well before you get there.

Questions about weight care.

How much does weight loss cost?+

Semaglutide is $299 a month and tirzepatide is $399 a month, with $100 off your first month for new patients. Two-month packages bring the monthly rate down to $275 and $375. The medication is included in that price.

Is the medication really included?+

Yes. There is no separate medication fee and no pharmacy bill to pay on top. If a GLP-1 is prescribed, it's prepared and shipped by a licensed compounding pharmacy as part of your program.

Semaglutide or tirzepatide?+

They work on different receptors. Semaglutide acts on GLP-1. Tirzepatide acts on both GLP-1 and GIP. Tirzepatide costs more. Which one suits you is a clinical decision your clinician makes with you, based on your history and your goals.

Who qualifies for a GLP-1?+

GLP-1 weight medications are generally considered for adults with a BMI of 30 or more, or 27 or more with a weight-related condition such as high blood pressure or prediabetes. Your clinician makes the final decision based on your full history.

How is it taken?+

Both are a once-weekly injection just under the skin that you do at home. After your medication arrives, a free session with the care team shows you exactly how.

What side effects are common?+

Nausea is the most common, mostly in the first weeks and after a dose increase, and it usually fades. Stepping the dose up slowly, eating smaller meals, and staying hydrated are the usual answers, and your clinician adjusts as you go.

Will I lose muscle?+

Some of the weight lost on a GLP-1 is lean mass. Eating enough protein and doing some strength training are the two most effective ways to protect it, and your clinician will talk through both.

Is this the same medication I've seen advertised?+

The active medications are semaglutide and tirzepatide, the same two molecules behind the GLP-1 treatments you have read about. Your clinician confirms which one suits you and which formulation you are prescribed, and it is dispensed through a licensed pharmacy. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.

Why does tirzepatide cost more?+

It acts on two gut hormones rather than one, and the medication itself costs more to source. Whether the difference is worth it for you is a conversation with your clinician.

How quickly will I see a change?+

Your dose starts low and steps up over the first weeks, so early changes are usually modest. Most people notice appetite changes before anything on the scale. Individual results vary.

Do I need insurance?+

No. Refuvia doesn't bill insurance, so there are no claims, no prior authorizations, and no denials. Most treatments are HSA and FSA eligible.

Do I need labs first?+

Not to begin. Your clinician may recommend the Refuvia Baseline Panel to see your metabolic markers before or during treatment, but it isn't a gate you have to clear before starting.

What happens if I stop?+

GLP-1 medications treat an ongoing condition, and appetite usually returns when they stop. Your clinician will talk through maintenance with you well before you get there.

An evening at home
RESTORE · TRANSFORM · THRIVE
Start with a real conversation.

Pick your program, or talk to the care team first and let them help you decide. The consult is free and it isn't a sales call.

An evening at home
RESTORE · TRANSFORM · THRIVE

Start with a real conversation.

Pick your program, or talk to the care team first. The consult is free and it isn't a sales call.

Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.

Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.

See the programsFree consult